Brusatol Enhances the Radiosensitivity of A549 Cells by Promoting ROS Production and Enhancing DNA Damage

NF-E2-related factor 2 (Nrf2) has been identified as a master regulatory factor in the protection of cells from oxidative and electrophilic stress. However, overexpression of Nrf2 in lung cancer may cause chemoresistance, as well as radioresistance. In this study, we examined the relationship betwee...

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Bibliographic Details
Main Authors: Xiaohui Sun, Qin Wang, Yan Wang, Liqing Du, Chang Xu, Qiang Liu
Format: Article
Language:English
Published: MDPI AG 2016-06-01
Series:International Journal of Molecular Sciences
Subjects:
ROS
Online Access:http://www.mdpi.com/1422-0067/17/7/997