Endothelium-Dependent Hyperpolarization (EDH) in Hypertension: The Role of Endothelial Ion Channels

Endothelium-Dependent Hyperpolarization (EDH) in Hypertension: The Role of Endothelial Ion Channels

Upon stimulation with agonists and shear stress, the vascular endothelium of different vessels selectively releases several vasodilator factors such as nitric oxide and prostacyclin. In addition, vascular endothelial cells of many vessels regulate the contractility of the vascular smooth muscle cell...

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Bibliographic Details
Main Authors: Kenichi Goto, Toshio Ohtsubo, Takanari Kitazono
Format: Article
Language:English
Published: MDPI AG 2018-01-01
Series:International Journal of Molecular Sciences
Subjects:
Ca2+-activated K+ channel
Ca2+-activated Cl− channel
endothelial function
endothelium-dependent hyperpolarization
endothelium-derived hyperpolarizing factor
hypertension
transient receptor potential vanilloid type 4 channel
Online Access:http://www.mdpi.com/1422-0067/19/1/315

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http://www.mdpi.com/1422-0067/19/1/315

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