A role for the PERIOD:PERIOD homodimer in the Drosophila circadian clock.
Circadian clocks in eukaryotes rely on transcriptional feedback loops, in which clock genes repress their own transcription resulting in molecular oscillations with a period of approximately 24 h. In Drosophila, the clock proteins Period (PER) and Timeless (TIM) operate in such a feedback loop, wher...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2009-04-01
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Series: | PLoS Biology |
Online Access: | http://europepmc.org/articles/PMC2671555 |