Knockdown of NPM1 by RNA Interference Inhibits Cells Proliferation and Induces Apoptosis in Leukemic Cell Line

<p>Nucleophosmin (NPM1) is an abundant and ubiquitously expressed phosphoprotein that is known to influence solid tumors progression. However, little is known about the role of NPM1 in leukemia. Here, we knocked down the <i>NPM1</i> expression by RNA interference to investigate the...

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Bibliographic Details
Main Author: Feng-Xian Qin, Hui-Yuan Shao, Xian-Chun Chen, Shi Tan, Hui-Juan Zhang, Zong-Yu Miao, Li Wang, Hui-Chen, Ling Zhang
Format: Article
Language:English
Published: Ivyspring International Publisher 2011-01-01
Series:International Journal of Medical Sciences
Online Access:http://www.medsci.org/v08p0287.htm