Concurrent Evaluation of the Expression and Methylation of Secreted Frizzled-Related Protein 2 along with Beta-Catenin Expression in Patients with non-M3 Acute Myeloid Leukemia

Concurrent Evaluation of the Expression and Methylation of Secreted Frizzled-Related Protein 2 along with Beta-Catenin Expression in Patients with non-M3 Acute Myeloid Leukemia

Background: Wnt signaling is a critical pathway for the development of acute myeloid leukemia (AML). Some studies have evaluated the expression or methylation of secreted frizzled-related protein 2 (SFRP2) as an antagonist and beta-catenin (β-catenin) as a critical mediator of this pathway. Since we...

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Bibliographic Details
Main Authors: Fatemeh Mirzaeyan, Bahram Chahardouli, Amin Mirzaeian, Nasrin Alizad Ghandforoush, Kamran Alimoghaddam, Shahrbano Rostami
Format: Article
Language:English
Published: Shiraz University of Medical Sciences 2021-05-01
Series:Iranian Journal of Medical Sciences
Subjects:
sfrp2 protein
humans
leukemia
myeloid
acute
beta catenin
wnt signaling pathway
Online Access:https://ijms.sums.ac.ir/article_47118_08d5f30085c92776f047417b3bffdf46.pdf

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https://ijms.sums.ac.ir/article_47118_08d5f30085c92776f047417b3bffdf46.pdf

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