Analysis of binding affinity and docking of novel fatty acid-binding protein (FABP) ligands

Fatty acid-binding proteins (FABPs) belong to a family of proteins that transports fatty acids in the cytosol and regulates cellular functions like membrane phospholipid synthesis, lipid metabolism, and mitochondrial β oxidation. In this study, we synthesized ten novel derivatives from BMS309403, a...

Full description

Bibliographic Details
Main Authors: Yasuharu Shinoda, Yifei Wang, Tetsunori Yamamoto, Hiroyuki Miyachi, Kohji Fukunaga
Format: Article
Language:English
Published: Elsevier 2020-08-01
Series:Journal of Pharmacological Sciences
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861320300499