Enhancing the Enzymatic Activity of a Heme-Dependent Peroxidase through Genetic Modification

A heme-dependent peroxidase (HDP) catalyzes the ortho-hydroxylation of l-tyrosine to l-3,4-dihydroxyphenylalanine (l-DOPA) in the presence of hydrogen peroxide. l-DOPA can be used for the treatment of Parkinson's disease. In this work, to improve the catalytic efficiency, the heme-dependent per...

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Bibliographic Details
Main Authors: Wei Liu, Rong Li, Dan Liu, Wei Feng
Format: Article
Language:English
Published: MDPI AG 2016-10-01
Series:Catalysts
Subjects:
Online Access:http://www.mdpi.com/2073-4344/6/11/166