Prenatal dexamethasone and postnatal high-fat diet have a synergistic effect of elevating blood pressure through a distinct programming mechanism of systemic and adipose renin–angiotensin systems

Prenatal dexamethasone and postnatal high-fat diet have a synergistic effect of elevating blood pressure through a distinct programming mechanism of systemic and adipose renin–angiotensin systems

Abstract Background Hypertension may result from high-fat (HF) diet induced-obesity and overexposure to glucocorticoids in utero. Recent studies demonstrated the potent contribution of adipose tissue’s renin-angiotensin system (RAS) to systemic RAS, which plays a key role in regulating blood pressur...

Full description

Bibliographic Details
Main Authors: Hong-Ren Yu, You-Lin Tain, Mao-Meng Tiao, Chih-Cheng Chen, Jiunn-Ming Sheen, I-Chun Lin, Shih-Wen Li, Ching-Chou Tsai, Yu-Ju Lin, Kai-Sheng Hsieh, Li-Tung Huang
Format: Article
Language:English
Published: BMC 2018-03-01
Series:Lipids in Health and Disease
Subjects:
Prenatal glucocorticoid
High-fat diet
Adipose tissue
Renin–angiotensin system
Online Access:http://link.springer.com/article/10.1186/s12944-018-0701-0

Internet

http://link.springer.com/article/10.1186/s12944-018-0701-0

Similar Items