Engineering Three-Dimensional Tumor Models to Study Glioma Cancer Stem Cells and Tumor Microenvironment

Engineering Three-Dimensional Tumor Models to Study Glioma Cancer Stem Cells and Tumor Microenvironment

Glioblastoma (GBM) is the most common and devastating primary brain tumor, leading to a uniform fatality after diagnosis. A major difficulty in eradicating GBM is the presence of microscopic residual infiltrating disease remaining after multimodality treatment. Glioma cancer stem cells (CSCs) have b...

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Bibliographic Details
Main Authors: Henry Ruiz-Garcia, Keila Alvarado-Estrada, Paula Schiapparelli, Alfredo Quinones-Hinojosa, Daniel M. Trifiletti
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Cellular Neuroscience
Subjects:
glioma
tumor microenvironment
stem cell
bioprinting
organoids
organ-on-a-chip
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2020.558381/full

Internet

https://www.frontiersin.org/article/10.3389/fncel.2020.558381/full

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