Configurational Entropy of Folded Proteins and Its Importance for Intrinsically Disordered Proteins

Configurational Entropy of Folded Proteins and Its Importance for Intrinsically Disordered Proteins

Many pairwise additive force fields are in active use for intrinsically disordered proteins (IDPs) and regions (IDRs), some of which modify energetic terms to improve the description of IDPs/IDRs but are largely in disagreement with solution experiments for the disordered states. This work considers...

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Bibliographic Details
Main Authors: Meili Liu, Akshaya K. Das, James Lincoff, Sukanya Sasmal, Sara Y. Cheng, Robert M. Vernon, Julie D. Forman-Kay, Teresa Head-Gordon
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:International Journal of Molecular Sciences
Subjects:
configurational entropy
force fields
intrinsically disordered proteins
Online Access:https://www.mdpi.com/1422-0067/22/7/3420

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https://www.mdpi.com/1422-0067/22/7/3420

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