Multiplex Zymography Captures Stage-specific Activity Profiles of Cathepsins K, L, and S in Human Breast, Lung, and Cervical Cancer
<p>Abstract</p> <p>Background</p> <p>Cathepsins K, L, and S are cysteine proteases upregulated in cancer and proteolyze extracellular matrix to facilitate metastasis, but difficulty distinguishing specific cathepsin activity in complex tissue extracts confounds scientif...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
BMC
2011-07-01
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Series: | Journal of Translational Medicine |
Online Access: | http://www.translational-medicine.com/content/9/1/109 |