Determination of amphotericin B in PLA-PEG blend nanoparticles by HPLC-PDA

In this work, we developed and validated an effective reversed-phase HPLC method with photodiode array (PDA) detection for the quantitative analysis of amphotericin B (AmB) in poly(lactide)-poly(ethylene glycol) (PLA-PEG) blend nanoparticles. Chromatographic runs were performed on a reverse phase C1...

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Bibliographic Details
Main Authors: Caroline Danziato Rodrigues, Najeh Maissar Khalil, Rubiana Mara Mainardes
Format: Article
Language:English
Published: Universidade de São Paulo 2014-12-01
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502014000400859&lng=en&tlng=en