Hyperbaric Oxygen Promotes Proximal Bone Regeneration and Organized Collagen Composition during Digit Regeneration.

Oxygen is critical for optimal bone regeneration. While axolotls and salamanders have retained the ability to regenerate whole limbs, mammalian regeneration is restricted to the distal tip of the digit (P3) in mice, primates, and humans. Our previous study revealed the oxygen microenvironment during...

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Bibliographic Details
Main Authors: Mimi C Sammarco, Jennifer Simkin, Alexander J Cammack, Danielle Fassler, Alexej Gossmann, Luis Marrero, Michelle Lacey, Keith Van Meter, Ken Muneoka
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4599941?pdf=render