Optimizing T Cell-Based Therapy for Glioblastoma

Evading T cell surveillance is a hallmark of cancer. Patients with solid tissue malignancy, such as glioblastoma (GBM), have multiple forms of immune dysfunction, including defective T cell function. T cell dysfunction is exacerbated by standard treatment strategies such as steroids, chemotherapy, a...

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Bibliographic Details
Main Authors: Aida Karachi, Farhad Dastmalchi, Saina Nazarian, Jianping Huang, Elias J. Sayour, Linchun Jin, Changlin Yang, Duane A. Mitchell, Maryam Rahman
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.705580/full