Caprylic acid suppresses inflammation via TLR4/NF-κB signaling and improves atherosclerosis in ApoE-deficient mice

Caprylic acid suppresses inflammation via TLR4/NF-κB signaling and improves atherosclerosis in ApoE-deficient mice

Abstract Background As reported previously by our group, medium-chain triglycerides can ameliorate atherosclerosis. Given that TLR4 is closely related to atherosclerosis, we hypothesized herein that caprylic acid (C8:0) would suppress inflammation via TLR4/NF-κB signaling and further promote the ame...

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Bibliographic Details
Main Authors: Xinsheng Zhang, Changyong Xue, Qing Xu, Yong Zhang, Huizi Li, Feng Li, Yinghua Liu, Changjiang Guo
Format: Article
Language:English
Published: BMC 2019-06-01
Series:Nutrition & Metabolism
Subjects:
Caprylic acid
Inflammation
TLR4
Atherosclerosis
apoE-deficient mice
Online Access:http://link.springer.com/article/10.1186/s12986-019-0359-2

Internet

http://link.springer.com/article/10.1186/s12986-019-0359-2

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