Sensitivity of IFN-gamma release assay to detect latent tuberculosis infection is retained in HIV-infected patients but dependent on HIV/AIDS progression.

Sensitivity of IFN-gamma release assay to detect latent tuberculosis infection is retained in HIV-infected patients but dependent on HIV/AIDS progression.

BACKGROUND:Detection and treatment of latent TB infection (LTBI) in HIV infected individuals is strongly recommended to decrease morbidity and mortality in countries with high levels of HIV. OBJECTIVE:To assess the validity of a newly developed in-house ELISPOT interferon-gamma release assay (IGRA)...

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Main Authors: Farba Karam, Fatou Mbow, Helen Fletcher, Cheikh S Senghor, Koura D Coulibaly, Andrea M LeFevre, Ndeye F Ngom Gueye, Tandakha Dieye, Papa S Sow, Souleymane Mboup, Christian Lienhardt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2174527?pdf=render

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http://europepmc.org/articles/PMC2174527?pdf=render

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