Sex differences in stroke outcome correspond to rapid and severe changes in gut permeability in adult Sprague-Dawley rats

Abstract Background Sex differences in experimental stroke outcomes are well documented, such that adult males have a greater infarct volume, increased stroke-induced mortality, and more severe sensory-motor impairment. Based on recent evidence that the gut is an early responder to stroke, the prese...

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Bibliographic Details
Main Authors: Yumna El-Hakim, Kathiresh Kumar Mani, Amir Eldouh, Sivani Pandey, Maria T. Grimaldo, Alan Dabney, Rachel Pilla, Farida Sohrabji
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Biology of Sex Differences
Subjects:
Online Access:https://doi.org/10.1186/s13293-020-00352-1