Subcutaneous administration of infliximab-attenuated silica-induced lung fibrosis

Subcutaneous administration of infliximab-attenuated silica-induced lung fibrosis

Objectives To investigate the influence of the anti-tumor necrosis factor-α infliximab (IFX) in the case of rats with silicosis. Material and Methods Forty-eight Wistar rats were randomly divided into 3 groups. The study group (N = 16) – silicosis was induced by intratracheal instillation of 50 mg...

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Bibliographic Details
Main Authors: Hua Zhang, Jun-Na Sui, Lei Gao, Jian Guo
Format: Article
Language:English
Published: Nofer Institute of Occupational Medicine 2018-07-01
Series:International Journal of Occupational Medicine and Environmental Health
Subjects:
infliximab
silicosis
TNF-α
rat model
NF-κB
iNOS
Online Access:http://www.journalssystem.com/ijomeh/Subcutaneous-Administration-of-Infliximab-Attenuated-silica-induced-lung-fibrosis,77973,0,2.html

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http://www.journalssystem.com/ijomeh/Subcutaneous-Administration-of-Infliximab-Attenuated-silica-induced-lung-fibrosis,77973,0,2.html

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