Novel approach to meta-analysis of microarray datasets reveals muscle remodeling-related drug targets and biomarkers in Duchenne muscular dystrophy.

Elucidation of new biomarkers and potential drug targets from high-throughput profiling data is a challenging task due to a limited number of available biological samples and questionable reproducibility of differential changes in cross-dataset comparisons. In this paper we propose a novel computati...

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Bibliographic Details
Main Authors: Ekaterina Kotelnikova, Maria A Shkrob, Mikhail A Pyatnitskiy, Alessandra Ferlini, Nikolai Daraselia
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-02-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC3271016?pdf=render