The Ameliorating Effect of Phenylsulfonamide Derivatives on Scopolamine-Induced Memory Impairment in Mice via Inhibition of mPGES-1

Our previous research showed that a novel series of phenylsulfonyl hydrazide derivatives reduced LPS-induced PGE<sub>2</sub> levels in RAW 264.7 macrophage cells via an inhibition of mPGES-1 enzyme. As a continuous work, new phenylsulfonamide derivatives (<b>5a</b>-<b>5...

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Bibliographic Details
Main Authors: Ki Deok Ryu, Yoon Hyoung Moon, Do Hyeong Ko, Kyung-Tae Lee, Jae Yeol Lee
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Proceedings
Subjects:
Online Access:https://www.mdpi.com/2504-3900/22/1/36