Confocal 3D DNA Cytometry: Assessment of Required Coefficient of Variation by Computer Simulation

Background: Confocal Laser Scanning Microscopy (CLSM) provides the opportunity to perform 3D DNA content measurements on intact cells in thick histological sections. So far, sample size has been limited by the time consuming nature of the technology. Since the power of DNA histograms to resolve diff...

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Bibliographic Details
Main Authors: Lennert S. Ploeger, Jeroen A.M. Beliën, Neal M. Poulin, William Grizzle, Paul J. van Diest
Format: Article
Language:English
Published: Hindawi Limited 2004-01-01
Series:Cellular Oncology
Online Access:http://dx.doi.org/10.1155/2004/350752