Efficacy of standard and low dose hydrochlorothiazide in the recurrence prevention of calcium nephrolithiasis (NOSTONE trial): protocol for a randomized double-blind placebo-controlled trial

Abstract Background Nephrolithiasis is a global healthcare problem with a current lifetime risk of 18.8% in men and 9.4% in women. Given the high cost of medical treatments and surgical interventions as well as the morbidity related to symptomatic stone disease, medical prophylaxis for stone recurre...

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Main Authors: Nasser A. Dhayat, Nicolas Faller, Olivier Bonny, Nilufar Mohebbi, Alexander Ritter, Lisa Pellegrini, Giulia Bedino, Carlo Schönholzer, Reto M. Venzin, Carina Hüsler, Irene Koneth, Rosaria Del Giorno, Luca Gabutti, Patrizia Amico, Michael Mayr, Urs Odermatt, Florian Buchkremer, Thomas Ernandez, Catherine Stoermann-Chopard, Daniel Teta, Felix Rintelen, Marie Roumet, Irina Irincheeva, Sven Trelle, Luca Tamò, Beat Roth, Bruno Vogt, Daniel G. Fuster
Format: Article
Language:English
Published: BMC 2018-12-01
Series:BMC Nephrology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12882-018-1144-6