Re-evaluating genetic variants identified in candidate gene studies of breast cancer risk using data from nearly 280,000 women of Asian and European ancestryResearch in context

Re-evaluating genetic variants identified in candidate gene studies of breast cancer risk using data from nearly 280,000 women of Asian and European ancestryResearch in context

Background: We previously conducted a systematic field synopsis of 1059 breast cancer candidate gene studies and investigated 279 genetic variants, 51 of which showed associations. The major limitation of this work was the small sample size, even pooling data from all 1059 studies. Thereafter, genom...

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Main Authors: Yaohua Yang, Xiang Shu, Xiao-ou Shu, Manjeet K. Bolla, Sun-Seog Kweon, Qiuyin Cai, Kyriaki Michailidou, Qin Wang, Joe Dennis, Boyoung Park, Keitaro Matsuo, Ava Kwong, Sue Kyung Park, Anna H. Wu, Soo Hwang Teo, Motoki Iwasaki, Ji-Yeob Choi, Jingmei Li, Mikael Hartman, Chen-Yang Shen, Kenneth Muir, Artitaya Lophatananon, Bingshan Li, Wanqing Wen, Yu-Tang Gao, Yong-Bing Xiang, Kristan J. Aronson, John J. Spinell, Manuela Gago-Dominguez, Esther M. John, Allison W. Kurian, Jenny Chang-Claude, Shou-Tung Chen, Thilo Dörk, D. Gareth R. Evans, Marjanka K. Schmidt, Min-Ho Shin, Graham G. Giles, Roger L. Milne, Jacques Simard, Michiaki Kubo, Peter Kraft, Daehee Kang, Douglas F. Easton, Wei Zheng, Jirong Long
Format: Article
Language:English
Published: Elsevier 2019-10-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396419306048

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http://www.sciencedirect.com/science/article/pii/S2352396419306048

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