Enhanced GABAergic network and receptor function in pediatric cortical dysplasia Type IIB compared with Tuberous Sclerosis Complex

Enhanced GABAergic network and receptor function in pediatric cortical dysplasia Type IIB compared with Tuberous Sclerosis Complex

Tuberous Sclerosis Complex (TSC) and cortical dysplasia Type IIB (CDIIB) share histopathologic features that suggest similar epileptogenic mechanisms. This study compared the morphological and electrophysiological properties of cortical cells in tissue from pediatric TSC (n=20) and CDIIB (n=20) pati...

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Bibliographic Details
Main Authors: Carlos Cepeda, Véronique M. André, Jason S. Hauptman, Irene Yamazaki, My N. Huynh, Julia W. Chang, Jane Y. Chen, Robin S. Fisher, Harry V. Vinters, Michael S. Levine, Gary W. Mathern
Format: Article
Language:English
Published: Elsevier 2012-01-01
Series:Neurobiology of Disease
Subjects:
Tuberous Sclerosis Complex
Cortical dysplasia
Electrophysiology
Synaptic activity
Patch clamp recordings
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996111002816

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http://www.sciencedirect.com/science/article/pii/S0969996111002816

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