Computing Individual Risks Based on Family History in Genetic Disease in the Presence of Competing Risks

When considering a genetic disease with variable age at onset (e.g., familial amyloid neuropathy, cancers), computing the individual risk of the disease based on family history (FH) is of critical interest for both clinicians and patients. Such a risk is very challenging to compute because 1 the gen...

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Bibliographic Details
Main Authors: Gregory Nuel, Alexandra Lefebvre, Olivier Bouaziz
Format: Article
Language:English
Published: Hindawi Limited 2017-01-01
Series:Computational and Mathematical Methods in Medicine
Online Access:http://dx.doi.org/10.1155/2017/9193630