Importance of finding the bona fide target of the Fanconi anemia pathway

Importance of finding the bona fide target of the Fanconi anemia pathway

Abstract Fanconi anemia (FA) is a rare genetic disease characterized by the deficiency of the cellular response and repair pathway for DNA interstrand crosslink (ICL) damage. Although recent studies have revealed the detailed molecular functions of FA proteins encoded by 22 genes, the mechanism of o...

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Bibliographic Details
Main Authors: Wataru Sakai, Kaoru Sugasawa
Format: Article
Language:English
Published: BMC 2019-03-01
Series:Genes and Environment
Subjects:
Fanconi anemia
Aldehyde
DNA damage
DNA repair
Online Access:http://link.springer.com/article/10.1186/s41021-019-0122-y

Internet

http://link.springer.com/article/10.1186/s41021-019-0122-y

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