EEF1D overexpression promotes osteosarcoma cell proliferation by facilitating Akt-mTOR and Akt-bad signaling

EEF1D overexpression promotes osteosarcoma cell proliferation by facilitating Akt-mTOR and Akt-bad signaling

Abstract Background Dysregulation of eukaryotic translation elongation factor 1 delta (EEF1D) in cancers has been reported; however, the role and mechanisms of EEF1D in osteosarcoma remain poorly understood. The aim of this study is to investigate the expression and role of EEF1D in osteosarcoma and...

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Bibliographic Details
Main Authors: Dong-dong Cheng, Shi-jie Li, Bin Zhu, Shu-min Zhou, Qing-cheng Yang
Format: Article
Language:English
Published: BMC 2018-03-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
EEF1D
Proliferation
Akt-mTOR signaling pathway
Akt-bad signaling pathway
Osteosarcoma
Online Access:http://link.springer.com/article/10.1186/s13046-018-0715-5

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http://link.springer.com/article/10.1186/s13046-018-0715-5

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