Deletion of <i>Kif5c</i> Does Not Alter Prion Disease Tempo or Spread in Mouse Brain

In prion diseases, the spread of infectious prions (PrPSc) is thought to occur within nerves and across synapses of the central nervous system (CNS). However, the mechanisms by which PrPSc moves within axons and across nerve synapses remain undetermined. Molecular motors, including kinesins and dyne...

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Bibliographic Details
Main Authors: Brent Race, Katie Williams, Chase Baune, James F. Striebel, Clayton W. Winkler, James A. Carroll, Sandra E. Encalada, Bruce Chesebro
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Viruses
Subjects:
PrP
Online Access:https://www.mdpi.com/1999-4915/13/7/1391