Sphingosine 1-phosphate protects against radiation-induced ovarian injury in female rats—impact on mitochondrial-related genes

Abstract The toxic effects of ionizing radiation on the gonads have been widely recognized. Sphingosine 1-phosphate (S1P) has a protective effect on ovarian injury, and although it is known that mitochondria are involved in this process, the specific mechanism is not fully understood. The present st...

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Bibliographic Details
Main Authors: Jiahui Zhao, Shuyun Zhang, Liesong Chen, Xiaolong Liu, Haihong Su, Lili Chen, Li Yang, Hong Zhang
Format: Article
Language:English
Published: BMC 2020-10-01
Series:Reproductive Biology and Endocrinology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12958-020-00659-z