A<sub>2A</sub> Receptor Homodimer-Disrupting Sequence Efficiently Delivered by a Protease-Resistant, Cyclic CPP Vector

A<sub>2A</sub> Receptor Homodimer-Disrupting Sequence Efficiently Delivered by a Protease-Resistant, Cyclic CPP Vector

G-protein-coupled receptors associate into dimers/oligomers whose function is not well understood. One approach to investigate this issue is to challenge oligomerization by peptides replicating transmembrane domains and to study their effect on receptor functionality. The disruptor peptides are typi...

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Bibliographic Details
Main Authors: Maria Gallo, Gemma Navarro, Rafael Franco, David Andreu
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:International Journal of Molecular Sciences
Subjects:
gpcr
adenosine receptors
homodimerization
gpcr function
disrupting peptides
trypsin
Online Access:https://www.mdpi.com/1422-0067/20/19/4937

Internet

https://www.mdpi.com/1422-0067/20/19/4937

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