HIV-1 integrase resistance associated mutations and the use of dolutegravir in Sub-Saharan Africa: a systematic review and meta-analysis protocol

HIV-1 integrase resistance associated mutations and the use of dolutegravir in Sub-Saharan Africa: a systematic review and meta-analysis protocol

Abstract Background Sub-Saharan Africa carries the greatest burden of HIV-infection with increasing drug resistance burden, which requires improved patient management and monitoring. Current WHO recommendations suggest transitioning to dolutegravir-based (adults) or raltegravir-based-regimens (neona...

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Bibliographic Details
Main Authors: Ezechiel Ngoufack Jagni Semengue, Maria Mercedes Santoro, Valantine Ngum Ndze, Beatrice Dambaya, Desiré Takou, Georges Teto, Alex Durand Nka, Lavinia Fabeni, Alison Wiyeh, Francesca Ceccherini-Silberstein, Vittorio Colizzi, Carlo-Federico Perno, Joseph Fokam
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Systematic Reviews
Subjects:
HIV-1
Integrase
Dolutegravir
Drug resistance
Sub-Saharan Africa
Online Access:http://link.springer.com/article/10.1186/s13643-020-01356-z

Internet

http://link.springer.com/article/10.1186/s13643-020-01356-z

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