Succinate Anaplerosis Has an Onco-Driving Potential in Prostate Cancer Cells

Succinate Anaplerosis Has an Onco-Driving Potential in Prostate Cancer Cells

Tumor cells display metabolic alterations when compared to non-transformed cells. These characteristics are crucial for tumor development, maintenance and survival providing energy supplies and molecular precursors. Anaplerosis is the property of replenishing the TCA cycle, the hub of carbon metabol...

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Bibliographic Details
Main Authors: Ana Carolina B. Sant’Anna-Silva, Juan A. Perez-Valencia, Marco Sciacovelli, Claude Lalou, Saharnaz Sarlak, Laura Tronci, Efterpi Nikitopoulou, Andras T. Meszaros, Christian Frezza, Rodrigue Rossignol, Erich Gnaiger, Helmut Klocker
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Cancers
Subjects:
cancer metabolism
prostate cancer
anaplerosis
mitochondria
succinate
Online Access:https://www.mdpi.com/2072-6694/13/7/1727

Internet

https://www.mdpi.com/2072-6694/13/7/1727

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