CTLA-4 blockade: therapeutic potential in cancer treatments
Ahmad A Tarhini, Fatima IqbalUniversity of Pittsburgh School of Medicine, Melanoma and Skin Cancer Program, Pittsburgh, PA, USAAbstract: Enhancing or prolonging T-cell activation by monoclonal antibodies (mAbs) blocking negative signaling receptors such as CTLA4 is one approach to overcoming tumor-i...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Dove Medical Press
2010-03-01
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| Series: | OncoTargets and Therapy |
| Online Access: | http://www.dovepress.com/ctla-4-blockade-therapeutic-potential-in-cancer-treatments-a4022 |