Gestational and early postnatal hypothyroidism alters VGluT1 and VGAT bouton distribution in the neocortex and hippocampus, and behavior in rats

Gestational and early postnatal hypothyroidism alters VGluT1 and VGAT bouton distribution in the neocortex and hippocampus, and behavior in rats

Thyroid hormones are fundamental for the expression of genes involved in the development of the CNS and their deficiency is associated with a wide spectrum of neurological diseases including mental retardation, attention deficit-hyperactivity disorder and autism spectrum disorders. We examined in ra...

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Bibliographic Details
Main Authors: Daniela eNavarro, Mayvi eAlvarado, Francisco eNavarrete, Manuel eGiner, Maria Jesus eObregon, Jorge eManzanares, Pere eBerbel
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-02-01
Series:Frontiers in Neuroanatomy
Subjects:
Cerebral Cortex
Hypothyroidism
Schizophrenia
Seizures
autism
prepulse inhibition
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnana.2015.00009/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnana.2015.00009/full

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