Down-regulation of transient receptor potential melastatin member 7 prevents migration and invasion of renal cell carcinoma cells via inactivation of the Src and Akt pathway

Down-regulation of transient receptor potential melastatin member 7 prevents migration and invasion of renal cell carcinoma cells via inactivation of the Src and Akt pathway

Purpose: Transient receptor potential melastatin member 7 (TRPM7), an ion channel and serine/threonine protein kinase, has been linked with distinct human malignancies. However, the role of TRPM7 in renal cell carcinoma (RCC) has not been investigated. The aim of this study is to determine whether T...

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Bibliographic Details
Main Authors: Yun-Sok Ha, Yeon-Yong Kim, Na Hee Yu, So Young Chun, Seock Hwan Choi, Jun Nyung Lee, Bum Soo Kim, Eun Sang Yoo, Tae Gyun Kwon
Format: Article
Language:English
Published: Korean Urological Association 2018-07-01
Series:Investigative and Clinical Urology
Subjects:
Carcinoma
renal cell
Neoplasm invasiveness
Neoplasm metastasis
Signal transduction
Online Access:https://www.icurology.org/Synapse/Data/PDFData/2020ICU/icu-59-263.pdf

Internet

https://www.icurology.org/Synapse/Data/PDFData/2020ICU/icu-59-263.pdf

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