Reformulating Pro-Oxidant Microglia in Neurodegeneration

Reformulating Pro-Oxidant Microglia in Neurodegeneration

In neurodegenerative diseases, microglia-mediated neuroinflammation and oxidative stress are central events. Recent genome-wide transcriptomic analyses of microglial cells under different disease conditions have uncovered a new subpopulation named disease-associated microglia (DAM). These studies ha...

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Bibliographic Details
Main Authors: Juan García-Revilla, Isabel M. Alonso-Bellido, Miguel A. Burguillos, Antonio J. Herrera, Ana M. Espinosa-Oliva, Rocío Ruiz, Luis Cruz-Hernández, Irene García-Domínguez, María A. Roca-Ceballos, Marti Santiago, José A. Rodríguez-Gómez, Manuel Sarmiento Soto, Rocío M. de Pablos, José L. Venero
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Journal of Clinical Medicine
Subjects:
microglia
oxidative stress
neurodegeneration
inflammation
disease-associated microglia (dam)
ros
rns
Online Access:https://www.mdpi.com/2077-0383/8/10/1719

Internet

https://www.mdpi.com/2077-0383/8/10/1719

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