SIGNIFICANCE OF SINGLE-NUCLEOTIDE POLYMORPHISMS 2578C>A AND +936C>T IN THE VEGF GENE FOR EFFICIENCY EVALUAT ION OF ANTICANCER IMMUNOTHERAPY IN PAT IENTS WITH METASTAT IC SKIN MELANOMA

SIGNIFICANCE OF SINGLE-NUCLEOTIDE POLYMORPHISMS 2578C>A AND +936C>T IN THE VEGF GENE FOR EFFICIENCY EVALUAT ION OF ANTICANCER IMMUNOTHERAPY IN PAT IENTS WITH METASTAT IC SKIN MELANOMA

Abstract. Increased VEGF levels in cancer patients may be associated with decreased number of dendritic cells (DCs) and lower DC function. We investigated whether VEGF gene polymorphisms -2578C>A (rs699947) and +936C>T (rs3025039) are associated with efficacy of autologous DC-based imm...

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Bibliographic Details
Main Authors: Yu. A. Khochenkova, G. Z. Chkadua, I. V. Samoylenko, T. F. Malivanova, I. N. Mikhailova, L. V. Demidov, E. V. Stepanova
Format: Article
Language:Russian
Published: SPb RAACI 2014-07-01
Series:Medicinskaâ Immunologiâ
Subjects:
vegf
snps
dendritic cells
anticancer immunotherapy
metastatic melanoma
Online Access:https://www.mimmun.ru/mimmun/article/view/671

Internet

https://www.mimmun.ru/mimmun/article/view/671

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