Clathrin- and dynamin-dependent endocytosis limits canonical NF-κB signaling triggered by lymphotoxin β receptor

Clathrin- and dynamin-dependent endocytosis limits canonical NF-κB signaling triggered by lymphotoxin β receptor

Abstract Background Lymphotoxin β receptor (LTβR) is a member of tumor necrosis factor receptor (TNFR) superfamily which regulates the immune response. At the cellular level, upon ligand binding, the receptor activates the pro-inflammatory NF-κB and AP-1 pathways. Yet, the intracellular distribution...

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Bibliographic Details
Main Authors: Małgorzata Maksymowicz, Marta Miączyńska, Magdalena Banach-Orłowska
Format: Article
Language:English
Published: BMC 2020-11-01
Series:Cell Communication and Signaling
Subjects:
Endocytosis
Lymphotoxin β receptor
NF-κB signaling
Receptor internalization
Dynamin
Clathrin-mediated endocytosis
Online Access:http://link.springer.com/article/10.1186/s12964-020-00664-0

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http://link.springer.com/article/10.1186/s12964-020-00664-0

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