Isotypes of autoantibodies against novel differential 4-hydroxy-2-nonenal-modified peptide adducts in serum is associated with rheumatoid arthritis in Taiwanese women

Isotypes of autoantibodies against novel differential 4-hydroxy-2-nonenal-modified peptide adducts in serum is associated with rheumatoid arthritis in Taiwanese women

Abstract Background Rheumatoid arthritis (RA) is an autoimmune disorder with systemic inflammation and may be induced by oxidative stress that affects an inflamed joint. Our objectives were to examine isotypes of autoantibodies against 4-hydroxy-2-nonenal (HNE) modifications in RA and associate them...

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Bibliographic Details
Main Authors: Kai-Leun Tsai, Che-Chang Chang, Yu-Sheng Chang, Yi-Ying Lu, I-Jung Tsai, Jin-Hua Chen, Sheng-Hong Lin, Chih-Chun Tai, Yi-Fang Lin, Hui-Wen Chang, Ching-Yu Lin, Emily Chia-Yu Su
Format: Article
Language:English
Published: BMC 2021-02-01
Series:BMC Medical Informatics and Decision Making
Subjects:
Rheumatoid arthritis
4-hydroxy-2-nonenal
Autoantibody isotype
Serum
Online Access:https://doi.org/10.1186/s12911-020-01380-y

Internet

https://doi.org/10.1186/s12911-020-01380-y

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