Serotonin 5-HT2B receptor antagonism is fundamental for protecting PC12 cells exposed to hydrogen peroxide

Serotonin 5-HT2B receptor antagonism is fundamental for protecting PC12 cells exposed to hydrogen peroxide

Objectives: According to our previous work, aripiprazole exerted a protective effect on hydrogen peroxide (H2O2)-treated PC12 cells; haloperidol did not. Because aripiprazole has distinct affinities to a set of neurotransmitter receptor subtypes, this study aimed to clarify which subtype is responsi...

Full description

Bibliographic Details
Main Authors: Takeshi Takayanagi, Yoko Kaneko S., Hiroshi Nagasaki, Yu Kodani, Akira Nakashima, Keiji Mori, Atsushi Suzuki, Mitsuyasu Itoh, Kazunao Kondo, Toshiharu Nagatsu, Miyuki Ota, Akira Ota
Format: Article
Language:English
Published: Fujita Medical Society 2016-03-01
Series:Fujita Medical Journal
Subjects:
hydrogen peroxide
pc12 cells
aripiprazole
serotonin 5-ht2b-receptor
dopamine d1-receptor
Online Access:https://www.jstage.jst.go.jp/article/fmj/1/1/1_1/_pdf/-char/en

Internet

https://www.jstage.jst.go.jp/article/fmj/1/1/1_1/_pdf/-char/en

Similar Items