Cyclic AMP Regulates Bacterial Persistence through Repression of the Oxidative Stress Response and SOS-Dependent DNA Repair in Uropathogenic Escherichia coli

Bacterial persistence is a transient, nonheritable physiological state that provides tolerance to bactericidal antibiotics. The stringent response, toxin-antitoxin modules, and stochastic processes, among other mechanisms, play roles in this phenomenon. How persistence is regulated is relatively ill...

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Bibliographic Details
Main Authors: Roberto C. Molina-Quiroz, Cecilia Silva-Valenzuela, Jennifer Brewster, Eduardo Castro-Nallar, Stuart B. Levy, Andrew Camilli, Michael S. Gilmore
Format: Article
Language:English
Published: American Society for Microbiology 2018-01-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/9/1/e02144-17