Lack of CCR5 modifies glial phenotypes and population of the nigral dopaminergic neurons, but not MPTP-induced dopaminergic neurodegeneration

Constitutive expression of C–C chemokine receptor (CCR) 5 has been detected in astrocytes, microglia and neurons, but its physiological roles in the central nervous system are obscure. The bidirectional interactions between neuron and glial cells through CCR5 and its ligands were thought to be cruci...

Full description

Bibliographic Details
Main Authors: Dong-Young Choi, Myung Koo Lee, Jin Tae Hong
Format: Article
Language:English
Published: Elsevier 2013-01-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996112002884