Fatty acid binding profile of the liver X receptor α

Fatty acid binding profile of the liver X receptor α

Liver X receptor (LXR)α is a nuclear receptor that responds to oxysterols and cholesterol overload by stimulating cholesterol efflux, transport, conversion to bile acids, and excretion. LXRα binds to and is regulated by synthetic (T-0901317, GW3695) and endogenous (oxysterols) ligands. LXRα activity...

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Bibliographic Details
Main Authors: Shimpi Bedi, Genesis Victoria Hines, Valery V. Lozada-Fernandez, Camila de Jesus Piva, Alagammai Kaliappan, S.Dean Rider, Jr., Heather A. Hostetler
Format: Article
Language:English
Published: Elsevier 2017-02-01
Series:Journal of Lipid Research
Subjects:
human liver X receptor α
peroxisome proliferator-activated receptor
transcription factor
endogenous ligand
medium-chain fatty acid
long-chain fatty acid
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520314206

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http://www.sciencedirect.com/science/article/pii/S0022227520314206

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