Design of Mannose-Coated Rifampicin nanoparticles modulating the immune response and Rifampicin induced hepatotoxicity with improved oral drug delivery

Design of Mannose-Coated Rifampicin nanoparticles modulating the immune response and Rifampicin induced hepatotoxicity with improved oral drug delivery

We have demonstrated the enhanced in vivo oral efficacy and enhanced hepatoprotective effects of preactivated thiolated chitosan (Cht) nanoparticles (NPs) for tuberculosis. The mannose anchored preactivated thiolated chitosan nanoparticles (MPTCht-NPs) were prepared and characterized in terms of the...

Full description

Bibliographic Details
Main Authors: Aisha Rauf, Tanveer A. Tabish, Ibrahim M Ibrahim, Muhammad Rauf ul Hassan, Sabira Tahseen, Mansoor Abdullah Sandhu, Gul Shahnaz, Abbas Rahdar, Magali Cucchiarini, Sadanand Pandey
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Arabian Journal of Chemistry
Subjects:
Biomaterials
Chitosan nanoparticles
Immunomodulation
Hepatoptotective
Rifampicin
Drug delivery
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535221003361

Internet

http://www.sciencedirect.com/science/article/pii/S1878535221003361

Similar Items