EZH2 negatively regulates PD-L1 expression in hepatocellular carcinoma

EZH2 negatively regulates PD-L1 expression in hepatocellular carcinoma

Abstract Background Accumulating studies suggest that targeting epigenetic modifications could improve the efficacy of tumor immunotherapy; however, the mechanisms underlying this phenomenon remain largely unknown. Here, we investigated the ability of the epigenetic modifier, enhancer of zeste 2 pol...

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Bibliographic Details
Main Authors: Gang Xiao, Li-Lian Jin, Chao-Qun Liu, Yong-Chun Wang, Ya-Ming Meng, Zhong-Guo Zhou, Jing Chen, Xing-Juan Yu, Yao-Jun Zhang, Jing Xu, Limin Zheng
Format: Article
Language:English
Published: BMJ Publishing Group 2019-11-01
Series:Journal for ImmunoTherapy of Cancer
Subjects:
EZH2
PD-L1
Epigenetics
Immunotherapy
Online Access:http://link.springer.com/article/10.1186/s40425-019-0784-9

Internet

http://link.springer.com/article/10.1186/s40425-019-0784-9

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