Propionibacterium acnes Enhances the Immunogenicity of HIVBr18 Human Immunodeficiency Virus-1 Vaccine

Propionibacterium acnes Enhances the Immunogenicity of HIVBr18 Human Immunodeficiency Virus-1 Vaccine

Immunization of BALB/c mice with HIVBr18, a DNA vaccine containing 18 CD4+ T cell epitopes from human immunodeficiency virus (HIV), induced specific CD4+ and CD8+ T cell responses in a broad, polyfunctional and persistent manner. With the aim of increasing the immunogenicity of this vaccine, the eff...

Full description

Bibliographic Details
Main Authors: Daniela Teixeira, Mayari Eika Ishimura, Juliana de Souza Apostólico, Jacqueline Miyuki Viel, Victor Cabelho Passarelli, Edecio Cunha-Neto, Daniela Santoro Rosa, Ieda Maria Longo-Maugéri
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Immunology
Subjects:
Propionibacterium acnes
adjuvant
human immunodeficiency virus-1
DNA vaccine
CD4+ T cell
immunomodulation
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00177/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2018.00177/full

Similar Items