High interstitial fluid pressure is associated with tumor-line specific vascular abnormalities in human melanoma xenografts.

PURPOSE: Interstitial fluid pressure (IFP) is highly elevated in many solid tumors. High IFP has been associated with low radiocurability and high metastatic frequency in human melanoma xenografts and with poor survival after radiation therapy in cervical cancer patients. Abnormalities in tumor vasc...

Full description

Bibliographic Details
Main Authors: Trude G Simonsen, Jon-Vidar Gaustad, Marit N Leinaas, Einar K Rofstad
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3386940?pdf=render