Variants identified in a GWAS meta-analysis for blood lipids are associated with the lipid response to fenofibrate.

A recent large-scale meta-analysis of genome-wide studies has identified 95 loci, 59 of them novel, as statistically significant predictors of blood lipid traits; we tested whether the same loci explain the observed heterogeneity in response to lipid-lowering therapy with fenofibrate. Using data fro...

Full description

Bibliographic Details
Main Authors: Stella Aslibekyan, Mark O Goodarzi, Alexis C Frazier-Wood, Xiaofei Yan, Marguerite R Irvin, Eric Kim, Hemant K Tiwari, Xiuqing Guo, Robert J Straka, Kent D Taylor, Michael Y Tsai, Paul N Hopkins, Stanley G Korenman, Ingrid B Borecki, Yii-Der I Chen, Jose M Ordovas, Jerome I Rotter, Donna K Arnett
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3485381?pdf=render