LRRK2 mediated Rab8a phosphorylation promotes lipid storage

LRRK2 mediated Rab8a phosphorylation promotes lipid storage

Abstract Background Several mutations in leucine rich repeat kinase 2 (LRRK2) gene have been associated with pathogenesis of Parkinson’s disease (PD), a neurodegenerative disorder marked by resting tremors, and rigidity, leading to Postural instability. It has been revealed that mutations that lead...

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Bibliographic Details
Main Authors: Miao Yu, Muhammad Arshad, Wenmin Wang, Dongyu Zhao, Li Xu, Linkang Zhou
Format: Article
Language:English
Published: BMC 2018-02-01
Series:Lipids in Health and Disease
Subjects:
LRRK2
Rab8a
Lipid droplets
Lipid storage
Parkinson’s disease
Online Access:http://link.springer.com/article/10.1186/s12944-018-0684-x

Internet

http://link.springer.com/article/10.1186/s12944-018-0684-x

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