Alzheimer’s Disease—A Panorama Glimpse

Alzheimer’s Disease—A Panorama Glimpse

The single-mutation of genes associated with Alzheimer’s disease (AD) increases the production of Aβ peptides. An elevated concentration of Aβ peptides is prone to aggregation into oligomers and further deposition as plaque. Aβ plaques and neurofibrillary tangles are two hallmarks of AD. In this rev...

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Bibliographic Details
Main Authors: Li Na Zhao, Lanyuan Lu, Lock Yue Chew, Yuguang Mu
Format: Article
Language:English
Published: MDPI AG 2014-07-01
Series:International Journal of Molecular Sciences
Subjects:
Alzheimer’s disease
amyloid peptide
amyloid β oligomer
tau protein
Aβ variants
Aβ polymorphism
pyroglutamate-modified amyloid beta peptides
Online Access:http://www.mdpi.com/1422-0067/15/7/12631

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http://www.mdpi.com/1422-0067/15/7/12631

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